Detection of Typhoid Carriers

Detection of typhoid carriers by agglutination tests.

Use of the Vi agglutination test in the detection of chronic carriers of Salmonella typhi (S. typhosa) first was suggested by Felix et al. (1935). Since that time study of the test by many workers has resulted in the accumulation of a voluminous literature which has been reviewed by Klein (1943), Felix (1951), Landy and Lamb (1953), and Spaun (1957). Bhatnagar et al. (1938) recommended the use ...

Typhoid Fever and Typhoid Carriers

New advances in the diagnosis of typhoid and detection of typhoid carriers.

For effective management of typhoid, diagnosis of the disease must be done with speed and accuracy. Development of such a test would require antigens that are specific for typhoid diagnosis. Attempts at finding the specific antigen have been carried out throughout the years. The finding of such an antigen can lead to carrier detection as well. Candidate antigens have been used in the developmen...

Ampicillin Treatment of Typhoid Carriers.

THE change in the clinical course of typhoid fever due to treatment with chloramphenicol has been one of the more dramatic triumphs of the antibiotic age. A prolonged fever has been converted into a short sharp febrile illness, so that the patient suffering from the disease, instead of being dangerously ill for several weeks, may well be sitting up in bed after three or four days on chloramphen...

Treatment of chronic typhoid carriers with ampicillin.

Ten chronic enteric typhoid carriers treated with oral ampicillin have been followed for 4 to 9 years and no relapses have occurred. Patients are probably cured if relapse does not occur within 2 years.